EPH receptor A1

Origem: Wikipédia, a enciclopédia livre.
Ir para: navegação, pesquisa
Estrutura tridimencional da EPHA1

EPH receptor A1 (ephrin type-A receptor 1) é uma proteína que em humanos é codificada pelo gene EPHA1.

Está relacionada com a Doença de Alzheimer e em vários tipos de câncer.1

Referências[editar | editar código-fonte]

  1. G1. Cientistas descobrem cinco novos genes de risco de Alzheimer. Acesso em 4 de abril de 2011

Leitura adicional[editar | editar código-fonte]

  • Flanagan JG, Vanderhaeghen P. (1998). "The ephrins and Eph receptors in neural development.". Annu. Rev. Neurosci. 21: 309–45. DOI:10.1146/annurev.neuro.21.1.309. PMID 9530499.
  • Zhou R. (1998). "The Eph family receptors and ligands.". Pharmacol. Ther. 77 (3): 151–81. DOI:10.1016/S0163-7258(97)00112-5. PMID 9576626.
  • Holder N, Klein R. (1999). "Eph receptors and ephrins: effectors of morphogenesis.". Development 126 (10): 2033–44. PMID 10207129.
  • Wilkinson DG. (2000). "Eph receptors and ephrins: regulators of guidance and assembly.". Int. Rev. Cytol. 196: 177–244. DOI:10.1016/S0074-7696(00)96005-4. PMID 10730216.
  • Xu Q, Mellitzer G, Wilkinson DG. (2001). "Roles of Eph receptors and ephrins in segmental patterning.". Philos. Trans. R. Soc. Lond., B, Biol. Sci. 355 (1399): 993–1002. DOI:10.1098/rstb.2000.0635. PMID 11128993.
  • Wilkinson DG. (2001). "Multiple roles of EPH receptors and ephrins in neural development.". Nat. Rev. Neurosci. 2 (3): 155–64. DOI:10.1038/35058515. PMID 11256076.
  • Hirai H, Maru Y, Hagiwara K, et al.. (1988). "A novel putative tyrosine kinase receptor encoded by the eph gene.". Science 238 (4834): 1717–20. DOI:10.1126/science.2825356. PMID 2825356.
  • Gale NW, Holland SJ, Valenzuela DM, et al.. (1996). "Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.". Neuron 17 (1): 9–19. DOI:10.1016/S0896-6273(00)80276-7. PMID 8755474.
  • Owshalimpur D, Kelley MJ. (1999). "Genomic structure of the EPHA1 receptor tyrosine kinase gene.". Mol. Cell. Probes 13 (3): 169–73. DOI:10.1006/mcpr.1999.0228. PMID 10369740.
  • Kalo MS, Pasquale EB. (outubro 1999). "Signal transfer by eph receptors". Cell and tissue research 298 (1): 1–9. PMID 10502115.
  • Coulthard MG, Lickliter JD, Subanesan N, et al.. (2002). "Characterization of the Epha1 receptor tyrosine kinase: expression in epithelial tissues.". Growth Factors 18 (4): 303–17. DOI:10.3109/08977190109029118. PMID 11519828.
  • Hillier LW, Fulton RS, Fulton LA, et al.. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. DOI:10.1038/nature01782. PMID 12853948.
  • Brandenberger R, Wei H, Zhang S, et al.. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. DOI:10.1038/nbt971. PMID 15146197.