Predefinição:PBB/3709

Inositol 1,4,5-trisphosphate receptor, type 2
Identificadores
Símbolos	ITPR2; CFAP48; IP3R2
IDs externos	OMIM: 600144 MGI: 99418 HomoloGene: 37593 IUPHAR: IP3R2 ChEMBL: 2512 GeneCards: ITPR2 Gene
Ontologia do gene Função molecular •inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity •calcium ion transmembrane transporter activity •phosphatidylinositol binding Componente celular •endoplasmic reticulum membrane •plasma membrane •cell cortex •membrane •integral component of membrane •platelet dense tubular network membrane •sarcoplasmic reticulum membrane •receptor complex Processo biológico •response to hypoxia •energy reserve metabolic process •transport •signal transduction •epidermal growth factor receptor signaling pathway •activation of phospholipase C activity •blood coagulation •fibroblast growth factor receptor signaling pathway •platelet activation •Fc-epsilon receptor signaling pathway •Fc-gamma receptor signaling pathway involved in phagocytosis •small molecule metabolic process •innate immune response •neurotrophin TRK receptor signaling pathway •inositol phosphate-mediated signaling •regulation of insulin secretion •calcium ion transmembrane transport •cellular response to cAMP •cellular response to ethanol Sources: Amigo / QuickGO
Ortólogos
Espécies	Humano	Rato
Entrez	3709	16439
Ensembl	ENSG00000123104	ENSMUSG00000030287
UniProt	Q14571	Q9Z329
RefSeq (mRNA)	NM_002223	NM_010586
RefSeq (proteína)	NP_002214	NP_034716
Localização (UCSC)	Chr 12: 26.49 – 26.99 Mb	Chr 6: 146.11 – 146.5 Mb
Busca PubMed	[1]	[2]