Predefinição:PBB/8074

Fator de crescimento fibroblástico 23
PDB rendering based on 2p39.
Estruturas disponíveis PDB Busca de ortólogos: PDBe, RCSB Lista de códigos PDB 2P39
Identificadores
Símbolos	FGF23; ADHR; HPDR2; HYPF; PHPTC
IDs externos	OMIM: 605380 MGI: 1891427 HomoloGene: 10771 GeneCards: FGF23 Gene
Ontologia do gene Função molecular •type 1 fibroblast growth factor receptor binding •growth factor activity Componente celular •extracellular region •extracellular space Processo biológico •phosphate-containing compound metabolic process •insulin receptor signaling pathway •fibroblast growth factor receptor signaling pathway •regulation of phosphate transport •positive regulation of vitamin D 24-hydroxylase activity •cell differentiation •negative regulation of bone mineralization •cellular phosphate ion homeostasis •vitamin D catabolic process •negative regulation of osteoblast differentiation •positive regulation of transcription, DNA-dependent •negative regulation of hormone secretion •phosphate ion homeostasis •positive regulation of ERK1 and ERK2 cascade •positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway Sources: Amigo / QuickGO
Padrões de expressão do ARN
Mais dados de expressão
Ortólogos
Espécies	Humano	Rato
Entrez	8074	64654
Ensembl	ENSG00000118972	ENSMUSG00000000182
UniProt	Q9GZV9	Q9EPC2
RefSeq (mRNA)	NM_020638.2	NM_022657.3
RefSeq (proteína)	NP_065689.1	NP_073148.1
Localização (UCSC)	Chr 12: 4.48 – 4.49 Mb	Chr 6: 127.07 – 127.08 Mb
Busca PubMed	[1]	[2]