Predefinição:PBB/959

CD154
Renderização com base em PDB 1aly.
Estruturas disponíveis PDB Busca de ortólogos: PDBe, RCSB Lista de códigos PDB 1ALY, 1I9R, 3LKJ, 3QD6
Identificadores
Símbolos	CD40LG; CD154; CD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP; gp39; hCD40L
IDs externos	OMIM: 300386 MGI: 88337 HomoloGene: 56 GeneCards: CD40LG Gene
Ontologia do gene Função molecular •cytokine activity •tumor necrosis factor receptor binding •CD40 receptor binding Componente celular •extracellular space •membrana plasmática •integral to plasma membrane •external side of plasma membrane •integral to membrane Processo biológico •positive regulation of immune response to tumor cell •anti-apoptosis •resposta inflamatória •leukocyte cell-cell adhesion •platelet activation •B cell differentiation •positive regulation of B cell proliferation •positive regulation of interferon-gamma production •positive regulation of interleukin-10 production •positive regulation of interleukin-12 production •B cell proliferation •isotype switching •positive regulation of MHC class II biosynthetic process •immunoglobulin secretion •regulation of immune response •regulation of immunoglobulin secretion •positive regulation of endothelial cell apoptotic process Sources: Amigo / QuickGO
Padrões de expressão do ARN
Mais dados de expressão
Ortólogos
Espécies	Humano	Rato
Entrez	959	21947
Ensembl	ENSG00000102245	ENSMUSG00000031132
UniProt	P29965	P27548
RefSeq (mRNA)	NM_000074.2	NM_011616.2
RefSeq (proteína)	NP_000065.1	NP_035746.2
Localização (UCSC)	Chr X: 135.73 – 135.74 Mb	Chr X: 57.21 – 57.22 Mb
Busca PubMed	[1]	[2]