Predefinição:PBB/3708

Inositol 1,4,5-trisphosphate receptor, type 1
PDB rendering based on 1n4k.
Estruturas disponíveis PDB Busca de ortólogos: PDBe, RCSB Lista de códigos PDB 1n4k, 1xzz
Identificadores
Símbolos	ITPR1; ACV; CLA4; INSP3R1; IP3R; IP3R1; PPP1R94; SCA15; SCA16; SCA29
IDs externos	OMIM: 147265 MGI: 96623 HomoloGene: 1673 IUPHAR: IP3R1 ChEMBL: 4046 GeneCards: ITPR1 Gene
Ontologia do gene Função molecular •intracellular ligand-gated calcium channel activity •inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity •protein binding •calcium ion transmembrane transporter activity •phosphatidylinositol binding Componente celular •nuclear inner membrane •nucleolus •endoplasmic reticulum •endoplasmic reticulum membrane •calcineurin complex •postsynaptic density •membrane •integral component of membrane •sarcoplasmic reticulum •platelet dense granule membrane •platelet dense tubular network •platelet dense tubular network membrane Processo biológico •response to hypoxia •energy reserve metabolic process •calcium ion transport •signal transduction •epidermal growth factor receptor signaling pathway •activation of phospholipase C activity •blood coagulation •fibroblast growth factor receptor signaling pathway •post-embryonic development •platelet activation •endoplasmic reticulum calcium ion homeostasis •Fc-epsilon receptor signaling pathway •Fc-gamma receptor signaling pathway involved in phagocytosis •small molecule metabolic process •innate immune response •neurotrophin TRK receptor signaling pathway •inositol phosphate-mediated signaling •regulation of insulin secretion •voluntary musculoskeletal movement •release of sequestered calcium ion into cytosol •intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress •calcium ion transmembrane transport Sources: Amigo / QuickGO
Padrões de expressão do ARN
Mais dados de expressão
Ortólogos
Espécies	Humano	Rato
Entrez	3708	16438
Ensembl	ENSG00000150995	ENSMUSG00000030102
UniProt	Q14643	P11881
RefSeq (mRNA)	NM_001099952	NM_010585
RefSeq (proteína)	NP_001093422	NP_034715
Localização (UCSC)	Chr 3: 4.54 – 4.89 Mb	Chr 6: 108.21 – 108.55 Mb
Busca PubMed	[1]	[2]