Predefinição:PBB/51185

Cereblon
Estruturas disponíveis PDB Busca de ortólogos: PDBe, RCSB Lista de códigos PDB 4M91
Identificadores
Símbolos	CRBN; MRT2; MRT2A
IDs externos	OMIM: 609262 MGI: 1913277 HomoloGene: 9461 GeneCards: CRBN Gene
Número EC	3.4.-
Ontologia do gene Função molecular •ATP-dependent peptidase activity •protein binding Componente celular •nucleus •nucleolus •cytoplasm •membrane •Cul4A-RING E3 ubiquitin ligase complex Processo biológico •ATP catabolic process •protein ubiquitination •negative regulation of protein homooligomerization •negative regulation of ion transmembrane transport •proteasome-mediated ubiquitin-dependent protein catabolic process •positive regulation of protein homodimerization activity Sources: Amigo / QuickGO
Ortólogos
Espécies	Humano	Rato
Entrez	51185	58799
Ensembl	ENSG00000113851	ENSMUSG00000005362
UniProt	Q96SW2	Q8C7D2
RefSeq (mRNA)	NM_001173482	NM_021449
RefSeq (proteína)	NP_001166953	NP_067424
Localização (UCSC)	Chr 3: 3.19 – 3.22 Mb	Chr 6: 106.78 – 106.8 Mb
Busca PubMed	[1]	[2]