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Revisão das 13h29min de 12 de outubro de 2009

Origin recognition complex, subunit 5-like (yeast)
Indicadores
Símbolo ORC5L
Símbolos alt. ORC5; ORC5P; ORC5T
HUGO 8491
Entrez 5001
OMIM 602331
RefSeq NP_00254
UniProt O43913
Outros dados
Locus Cr. 7 [1]

Origin recognition complex, subunit 5-like (yeast) também conhecido como ORC5L, é um gene humano.[1]

Interações

ORC5L mostrou interação com ORC1L,[2] ORC2L,[2][3][4][5] MCM7,[2] ORC4L,[2][3][4] ORC3L,[2][4][6][5] MCM2,[2] MCM4[2] e MCM3.[2]

Referências

  1. ↑ «Entrez Gene: ORC5L origin recognition complex, subunit 5-like (yeast)» 
  2. ↑ a b c d e f g h Kneissl, Margot; Pütter Vera, Szalay Aladar A, Grummt Friedrich (2003). «Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells». England. J. Mol. Biol. 327 (1): 111-28. ISSN 0022-2836. PMID 12614612  Parâmetro desconhecido |quotes= ignorado (|titulolivro=) sugerido (ajuda);
  3. ↑ a b Quintana, D G; Thome K C, Hou Z H, Ligon A H, Morton C C, Dutta A (1998). «ORC5L, a new member of the human origin recognition complex, is deleted in uterine leiomyomas and malignant myeloid diseases». UNITED STATES. J. Biol. Chem. 273 (42): 27137-45. ISSN 0021-9258. PMID 9765232  Parâmetro desconhecido |quotes= ignorado (|titulolivro=) sugerido (ajuda);
  4. ↑ a b c Dhar, S K; Delmolino L, Dutta A (2001). «Architecture of the human origin recognition complex». United States. J. Biol. Chem. 276 (31): 29067-71. ISSN 0021-9258. PMID 11395502. doi:10.1074/jbc.M103078200  Parâmetro desconhecido |quotes= ignorado (|titulolivro=) sugerido (ajuda);
  5. ↑ a b Vashee, S; Simancek P, Challberg M D, Kelly T J (2001). «Assembly of the human origin recognition complex». United States. J. Biol. Chem. 276 (28): 26666-73. ISSN 0021-9258. PMID 11323433. doi:10.1074/jbc.M102493200  Parâmetro desconhecido |quotes= ignorado (|titulolivro=) sugerido (ajuda);
  6. ↑ Pinto, S; Quintana D G, Smith P, Mihalek R M, Hou Z H, Boynton S, Jones C J, Hendricks M, Velinzon K, Wohlschlegel J A, Austin R J, Lane W S, Tully T, Dutta A (1999). «latheo encodes a subunit of the origin recognition complex and disrupts neuronal proliferation and adult olfactory memory when mutant». UNITED STATES. Neuron. 23 (1): 45-54. ISSN 0896-6273. PMID 10402184  Parâmetro desconhecido |quotes= ignorado (|titulolivro=) sugerido (ajuda);

Leitura de apoio

  • Maruyama K, Sugano S (1994). «Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.». Gene. 138 (1-2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8 
  • Klemm RD, Austin RJ, Bell SP (1997). «Coordinate binding of ATP and origin DNA regulates the ATPase activity of the origin recognition complex.». Cell. 88 (4): 493–502. PMID 9038340. doi:10.1016/S0092-8674(00)81889-9 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). «Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.». Gene. 200 (1-2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3 
  • Ishiai M, Dean FB, Okumura K; et al. (1998). «Isolation of human and fission yeast homologues of the budding yeast origin recognition complex subunit ORC5: human homologue (ORC5L) maps to 7q22.». Genomics. 46 (2): 294–8. PMID 9417919. doi:10.1006/geno.1997.5003 
  • Quintana DG, Thome KC, Hou ZH; et al. (1998). «ORC5L, a new member of the human origin recognition complex, is deleted in uterine leiomyomas and malignant myeloid diseases.». J. Biol. Chem. 273 (42): 27137–45. PMID 9765232. doi:10.1074/jbc.273.42.27137 
  • Tugal T, Zou-Yang XH, Gavin K; et al. (1999). «The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p.». J. Biol. Chem. 273 (49): 32421–9. PMID 9829972. doi:10.1074/jbc.273.49.32421 
  • Jiang W, McDonald D, Hope TJ, Hunter T (1999). «Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication.». EMBO J. 18 (20): 5703–13. PMID 10523313. doi:10.1093/emboj/18.20.5703 
  • Thome KC, Dhar SK, Quintana DG; et al. (2001). «Subsets of human origin recognition complex (ORC) subunits are expressed in non-proliferating cells and associate with non-ORC proteins.». J. Biol. Chem. 275 (45): 35233–41. PMID 10954718. doi:10.1074/jbc.M005765200 
  • Vashee S, Simancek P, Challberg MD, Kelly TJ (2001). «Assembly of the human origin recognition complex.». J. Biol. Chem. 276 (28): 26666–73. PMID 11323433. doi:10.1074/jbc.M102493200 
  • Fröhling S, Nakabayashi K, Scherer SW; et al. (2001). «Mutation analysis of the origin recognition complex subunit 5 (ORC5L) gene in adult patients with myeloid leukemias exhibiting deletions of chromosome band 7q22.». Hum. Genet. 108 (4): 304–9. PMID 11379876. doi:10.1007/s004390100498 
  • Dhar SK, Delmolino L, Dutta A (2001). «Architecture of the human origin recognition complex.». J. Biol. Chem. 276 (31): 29067–71. PMID 11395502. doi:10.1074/jbc.M103078200 
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). «Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.». Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932. doi:10.1073/pnas.242603899 
  • Kneissl M, Pütter V, Szalay AA, Grummt F (2003). «Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells.». J. Mol. Biol. 327 (1): 111–28. PMID 12614612. doi:10.1016/S0022-2836(03)00079-2 
  • Scherer SW, Cheung J, MacDonald JR; et al. (2003). «Human chromosome 7: DNA sequence and biology.». Science. 300 (5620): 767–72. PMID 12690205. doi:10.1126/science.1083423 


  • Hillier LW, Fulton RS, Fulton LA; et al. (2003). «The DNA sequence of human chromosome 7.». Nature. 424 (6945): 157–64. PMID 12853948. doi:10.1038/nature01782 
  • Ramachandran N, Hainsworth E, Bhullar B; et al. (2004). «Self-assembling protein microarrays.». Science. 305 (5680): 86–90. PMID 15232106. doi:10.1126/science.1097639 
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). «The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).». Genome Res. 14 (10B): 2121–7. PMID 15489334. doi:10.1101/gr.2596504 



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