Warren Alpert Foundation Prize

O Warren Alpert Foundation Prize é uma premiação concedida anualmente a cientistas cujo trabalho levou à prevenção, cura ou tratamento de doenças humanas, e/ou cujas pesquisas constituem uma descoberta científica seminal com grandes expectativas de revolucionar o entendimento ou habilidade para tratar doenças. O prêmio foi estabelecido em 1987 pelo filantropo Warren Alpert e pela Warren Alpert Foundation.

O prêmio é administrado conjuntamente pela Harvard Medical School em Boston, Massachusetts e a Warren Alpert Foundation, localizada em Providence, Rhode Island. Um simpósio anual ocorre na Harvard Medical School, onde os laureados apresentam seus trabalhos. O prêmio consiste em uma gratificação monetária de US$ 500.000, uma citação e uma placa.

Recipientes

Ano	Recipiente	Citação	Nationalidade
1987	Kenneth Murray, Universidade de Edimburgo	Pelo desenvolvimento de uma vacina contra hepatite B.	Escócia
1988	Louis Martens Kunkel, Harvard Medical School	Pela descoberta do gene associado com a forma maior da distrofia muscular.	Estados Unidos
1989	Yuet Wai Kan, Universidade da Califórnia em São Francisco	Por triagem genética pré-natal de doenças sanguíneas.	Estados Unidos
1990	Ano sem premiação.
1991	David Cushman e Miguel Ondetti, Bristol Myers-Squibb	Pela terapia do inibidor da enzima de conversão da angiotensina.	Estados Unidos Argentina
1992	Roscoe Brady, National Institutes of Health	Pelo tratamento da doença de Gaucher.	Estados Unidos
1993	Stuart Orkin, Harvard Medical School.	Por mecanismos genéticos e moleculares da beta-talassemia e outras desordens sanguíneas.	Estados Unidos
1994	J.R. Warren, Royal Perth Hospital e Barry Marshall, University of Virginia	Por relacionar úlceras com a bactéria helicobacter pylori.	Austrália
1995	John A. Clements, University of California, San Francisco	Pela descoberta da surfactante pulmonar e o desenvolvimento da terapia sulfactante pulmonar.	Estados Unidos
1996	Leo Sachs, Weizmann Institute of Science e Donald Metcalf, University of Melbourne	Pela descoberta dos fatores de crescimento das células sanguineas.	Israel Austrália
1997	Robert Gallo, University of Maryland School of Medicine, and Luc Montagnier, Queens College, New York	Por isolar o vírus da imunodeficiência humana.	Estados Unidos França
1998	K. Frank Austen, Harvard Medical School	Por elucidar a ação do leucotrieno na asma.	Estados Unidos
1999	Michael S. Brown e Joseph L. Goldstein, University of Texas Southwestern Medical School, Akira Endo (biochemist), Tokyo Noko University	For Development of HMG-CoA reductase inhibitors.	Estados Unidos Japão
2000	David Baltimore, California Institute of Technology, Brian Druker, Oregon Health Sciences University, Nicholas Lydon, Amgen, Inc., Alex Matter, Novartis Pharma AG, and Owen Witte, University of California, Los Angeles.	For Development of Abl kinase inhibitors for use in the treatment of chronic myelogenous leukemia	Estados UnidosSwitzerland
2001	Eugene Braunwald, Harvard Medical School, and Barry Coller, Rockefeller University School of Medicine.	For work in cardiac physiology and pathophysiology, leading to the use of monoclonal antibodies to platelet surface antigens in antithrombotic therapy.	Estados Unidos
2002	Alfred Sommer, Johns Hopkins University Bloomberg School of Public Health	For epidemiologic insight into the effects of Vitamin A deficiency, and the resulting reduction in childhood mortality worldwide.	Estados Unidos
2003	Sidney Pestka, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, David Goeddel, Tularik, Inc., and Charles Weissmann, Imperial College School of Medicine, London	For purification and characterization of interferon alpha; cloning of the human interferon alpha gene and mass production of recombinant interferon alpha for cancer treatment and treatment of hepatitis C.	Reino Unido Estados Unidos
2004	Susan Band Horwitz, Albert Einstein College of Medicine	For her seminal contributions to the understanding of how the antitumor agent Taxol kills cancer cells.	United States
2005	M. Judah Folkman, Harvard Medical School e Boston Children's Hospital	Pela descoberta do tumor angiogênese, e por trabalho pioneiro no desenvolvimento de terapias antiangiogênicas para o câncer.	Estados Unidos
2006	Dennis Slamon, UCLA, Robert Weinberg, MIT, Michael Shepard, Receptor BioLogix, Inc, and Axel Ullrich, Center for Molecular Medicine,	For their work in identifying HER-2/neu as an oncogene and development of the anti-HER-2/neu monoclonal antibody Herceptin for breast cancer therapy.	Estados Unidos Alemanha
2007	Harald zur Hausen e Lutz Gissmann, German Cancer Research Center	For work leading to the development of a vaccine against human papillomavirus.	Alemanha
2008	Dr. Lloyd Aiello, Joslin Diabetes Center	For the discovery, characterization and implementation of laser panretinal photocoagulation, which is used to treat proliferative diabetic retinopathy	Estados Unidos
2009-2010	Dr. Howard Green, Harvard Medical School	For development of methodologies for the expansion and differentiation of human keratinocyte stem cells for permanent skin restoration in victims of extensive burns.	Estados Unidos
2011	Dr. Alain Carpentier, Hôpital européen Georges-Pompidou, and Dr. Robert Langer, Massachusetts Institute of Technology	For their application of bioengineering principles to fundamental improvements in human health.	Estados Unidos França
2012	Dr. Julian Adams, Infinity Pharmaceuticals, Dr. Kenneth C. Anderson, Dana-Farber Cancer Institute, Dr. Alfred L. Goldberg, Harvard Medical School, and Dr. Paul G. Richardson, Dana-Farber Cancer Institute	For the discovery, preclinical and clinical development of bortezomib to FDA approval and front line therapy for the treatment of patients with multiple myeloma.	Estados Unidos
2013	Dr. David Botstein, Princeton University, Ronald W. Davis, Stanford University School of Medicine, and Dr. David Hogness, Stanford University School of Medicine	For their seminal contributions to the concepts and methods of creating a genetic map in the human, and of positional cloning, leading to the identification of thousands of human disease genes and ushering in the era of human genetics.	Estados Unidos
2014	Dr. Oleh Hornykiewicz, Medical University of Vienna, Roger A. Nicoll, University of California, San Francisco, Dr. Solomon H. Snyder, Johns Hopkins School of Medicine	For seminal contributions to our understanding of neurotransmission and neurodegeneration.	Áustria Estados Unidos
2015	Ruth Sonntag Nussenzweig e Victor Nussenzweig, NYU Langone Medical Center, Tu Youyou of the China Academy of Chinese Medical Sciences, Beijing	For their pioneering discoveries in chemistry and parasitology, and their personal commitment to translating these discoveries into effective chemotherapeutic and vaccine-based approaches to controlling malaria	Brasil China
2016	Rodolphe Barrangou, North Carolina State University, Philippe Horvath, DuPont, Jennifer Doudna, University of California, Berkeley, Emmanuelle Charpentier, Max Planck Institute for Infection Biology and Umeå University, Virginijus Šikšnys, Vilnius University Institute of Biotechnology	For their remarkable contributions to the understanding of the CRISPR bacterial defense system and the revolutionary discovery that it can be adapted for genome editing	FrançaEstados Unidos Lituânia
2017	Arlene Sharpe, Harvard Medical School, Gordon Freeman, Dana Farber Cancer Institute, Lieping Chen, Yale University, James P. Allison, University of Texas and Anderson Cancer Center, Tasuku Honjo, Kyoto University	For their collective contributions to the pre-clinical foundation and development of immune checkpoint blockade, a novel form of cancer therapy that has transformed the landscape of cancer treatment.	Estados UnidosJapão
2018	Francis Collins, Paul Negulescu, Bonnie Ramsey, Tsui Lap-Chee, Michael Welsh	For identifying faulty gene behind devastating disease, development of precision-targeted therapies	Estados UnidosChina
2019	Edward Boyden, Karl Deisseroth, Peter Hegemann, Gero Miesenböck	Por trabalho pioneiro na área da optogenética, uma técnica revolucionária que usa a luz e modificações genéticas para controlar as células do cérebro.	United States Germany Austria

Ligações externas

• Harvard Medical School
• Warren Alpert Foundation Prize